Chronic fatigue syndrome

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In medicine, chronic fatigue syndrome is "a syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and fibromyalgia."[1][2]

Etiology

Xenotropic murine leukemia virus-related virus (XMRV), a human gammaretrovirus, may contribute to infection.[3]In one study, the virus was found "in nearly 98 percent of about 300 patients with the syndrome" while only 3.7 percent of 218 healthy people were infected.[4]

References

  1. Anonymous (2024), Chronic fatigue syndrome (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A (1994). "The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group.". Ann Intern Med 121 (12): 953-9. PMID 7978722.
  3. Lombardi, Vincent C.; Francis W. Ruscetti, Jaydip Das Gupta, Max A. Pfost, Kathryn S. Hagen, Daniel L. Peterson, Sandra K. Ruscetti, Rachel K. Bagni, Cari Petrow-Sadowski, Bert Gold, Michael Dean, Robert H. Silverman, Judy A. Mikovits (2009-10-08). "Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome". Science: 1179052. DOI:10.1126/science.1179052. Retrieved on 2009-10-09. Research Blogging.
  4. Grady, Denise. Virus Is Found in Many With Chronic Fatigue Syndrome, The New York Times, 2009-10-09. Retrieved on 2009-10-09.