Corticosteroids, also called adrenal cortex hormones, are steroids mainly produced by the adrenal cortex.
There are three major groups of corticosteroids.
The 17-Ketosteroids are the sex steroids and are mainly produced in the zona reticularis layer (the innermost layer of the adrenal gland) of the adrenal cortex.
Glucocorticoids affect carbohydrate metabolism and inflammation are mainly produced in the zona fasciculata of the adrenal cortex. The naturally occurring glucocorticoids include hydrocortisone (also called cortisol). The normal adult secretes 10 to 20 mg of cortisol per day.
The hydroxycorticosteroids are mostly the mineralocorticoids and are mainly produced in the zona glomerulosa layer (the outermost layer of the adrenal gland) of the adrenal cortex. The naturally occurring mineralocorticoids include aldosterone and deoxycorticosterone.
|Adapted from Cancer Medicine and US Pharmacist|
Corticosteroids are beneficial in treated selected infections
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