Uremia: Difference between revisions
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'''Uremia''' is defined as "the illness accompanying [[chronic kidney disease|kidney failure]] that cannot be explained by derangements in extracellular volume, inorganic ion concentrations, or lack of known renal synthetic products."<ref name="pmid17898101">{{cite journal |author=Meyer TW, Hostetter TH |title=Uremia |journal=N. Engl. J. Med. |volume=357 |issue=13 |pages=1316–25 |year=2007 |pmid=17898101 |doi=10.1056/NEJMra071313}}</ref> | '''Uremia''' is defined as "the illness accompanying [[chronic kidney disease|kidney failure]] that cannot be explained by derangements in extracellular volume, inorganic ion concentrations, or lack of known renal synthetic products."<ref name="pmid17898101">{{cite journal |author=Meyer TW, Hostetter TH |title=Uremia |journal=N. Engl. J. Med. |volume=357 |issue=13 |pages=1316–25 |year=2007 |pmid=17898101 |doi=10.1056/NEJMra071313}}</ref> | ||
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Subtle cognitive dysfunction may occur when the [[glomerular filtration rate]] falls below 30 to 60 ml per minute per 1.73 m<sup>2</sup>.<ref name="pmid17898101"/> | Subtle cognitive dysfunction may occur when the [[glomerular filtration rate]] falls below 30 to 60 ml per minute per 1.73 m<sup>2</sup>.<ref name="pmid17898101"/> | ||
Insulin resistance may occur when the [[glomerular filtration rate]] falls below 50 ml per minute per 1.73 m<sup>2</sup>.<ref name="pmid17898101"/> | |||
==Treatment== | ==Treatment== | ||
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==Prognosis== | ==Prognosis== | ||
The | The five year survival for patients starting both hemodialysis and peritoneal dialysis is about 35%.<ref name="pmid17898101"/> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 10:27, 13 December 2009
Uremia is defined as "the illness accompanying kidney failure that cannot be explained by derangements in extracellular volume, inorganic ion concentrations, or lack of known renal synthetic products."[1]
Signs and symptoms
Signs such as well-being, fatigue, and reduced stamina may occur when the glomerular filtration rate falls below 50 to 60 ml per minute per 1.73 m2.[1]
Subtle cognitive dysfunction may occur when the glomerular filtration rate falls below 30 to 60 ml per minute per 1.73 m2.[1]
Insulin resistance may occur when the glomerular filtration rate falls below 50 ml per minute per 1.73 m2.[1]
Treatment
Treatment options include hemodialysis, peritoneal dialysis, or renal transplant. Hemodialysis is usually done three times a week and each session removes about tho-thirds of the total-body urea content.[1]
Prognosis
The five year survival for patients starting both hemodialysis and peritoneal dialysis is about 35%.[1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Meyer TW, Hostetter TH (2007). "Uremia". N. Engl. J. Med. 357 (13): 1316–25. DOI:10.1056/NEJMra071313. PMID 17898101. Research Blogging.