Spironolactone: Difference between revisions
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[[Image:Spironolactone DEVolk.jpg|right|thumb|150px|{{#ifexist:Template:Spironolactone DEVolk.jpg/credit|{{Spironolactone DEVolk.jpg/credit}}<br/>|}}Spironolactone, an aldosterone antagonist.]] | |||
'''Spironolactone''' is an [[aldosterone]] antagonist used to treat [[edema]] associated with [[congestive heart failure]], [[nephrotic syndrome]] or [[hepatic cirrhosis]]. Although it can also be used treat [[hirsutism]] and [[acne]] by effecting the [[endocrine system]], such use can lead to adverse side effects. | '''Spironolactone''' is an [[aldosterone]] antagonist used to treat [[edema]] associated with [[congestive heart failure]], [[nephrotic syndrome]] or [[hepatic cirrhosis]]. Although it can also be used treat [[hirsutism]] and [[acne]] by effecting the [[endocrine system]], such use can lead to adverse side effects. | ||
Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15, | Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15, | ||
Revision as of 10:45, 22 January 2008
Spironolactone is an aldosterone antagonist used to treat edema associated with congestive heart failure, nephrotic syndrome or hepatic cirrhosis. Although it can also be used treat hirsutism and acne by effecting the endocrine system, such use can lead to adverse side effects. Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15, 16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate.
trade names
- Abbolactone
- Acelat
- Aldace
- Aldactazide
- Aldactide
- Aldactone
- Aldactone A
- Alderon
- Aldopur
- Almatol
- Altex
- Aquareduct
- Deverol
- Diatensec
- Dira
- Duraspiron
- Espironolactona [INN-Spanish]
- Euteberol
- Lacalmin
- Lacdene
- Laractone
- Melarcon
- Nefurofan
- Osyrol
- SNL
- Sagisal
- Sincomen
- Spiresis
- Spiretic
- Spiridon
- Spiro-Tablinen
- Spiroctan
- Spiroctanie
- Spiroderm
- Spirolactone
- Spirolakton
- Spirolang
- Spirolone
- Spirone
- Spironocompren
- Spironolactone A
- Spironolactone [BAN:INN:JAN]
- Spironolactonum [INN-Latin]
- Spironolattone [DCIT]
- Sprioderm
- Supra-puren
- Suracton
- Uractone
- Urusonin
- Verospiron
- Verospirone
- Verospirone Opianin
- Xenalon
references
Material adapted from Drug Bank at (http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01234)