Darusentan: Difference between revisions

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imported>David E. Volk
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{{Chem infobox
{{Chem infobox
|align=right
|align=right
|image=[[Image:Darusentan.png|center|thumb|350px]]  
|image=[[Image:Darusentan.png|center|thumb|300px]]  
|width=350px
|width=300px
|molname=darusentan
|molname= darusentan
|synonyms=  
|synonyms=  
|molformula= C<sub>22</sub>H<sub>22</sub>N<sub>2</sub>O<sub>6</sub>  
|molformula= C<sub>22</sub>H<sub>22</sub>N<sub>2</sub>O<sub>6</sub>  

Revision as of 08:42, 19 September 2009

Darusentan.png
darusentan
IUPAC name: (2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic

acid

Synonyms:
Formula: C22H22N2O6

 Uses: hypertension

 Properties:

 Hazards: see side effects & drug interactions

Mass (g/mol): CAS #:
410.41988 171714-84-4


In medicine, darusentan is a medication for treating hypertension that is a selective endothelin type A antagonist. It is a vasodilator.[1]

Drug toxicity

Fluid retention is the most common drug toxicity.[1]

References

  1. 1.0 1.1 Weber MA et al. (2009) A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial. Lancet DOI:10.1016/S0140-6736(09)61500-2