Bariatric surgery/Bibliography

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Le Roux CW et al. (2006) Gut Hormone Profiles Following Bariatric Surgery Favor an Anorectic State, Facilitate Weight Loss, and Improve Metabolic Parameters. Ann Surg. 243: 108–114. (We examined meal-stimulated responses of insulin, ghrelin, peptide YY (PYY), glucagon-like-peptide-1 (GLP-1), and pancreatic polypeptide (PP) in humans and rodents following different bariatric surgical techniques... exogenous PYY reduced food intake and blockade of endogenous PYY increased food intake. Thus, higher plasma PYY following JIB may contribute to reduced food intake and contribute to weight loss.)

Review Articles

  1. Magni P. et al. (2009) Feeding behavior in mammals including humans. Ann.N.Y.Acad.Sci. 1163:221-232. PMID 19456343

Buchwald, H.; Avidor, Y.; Braunwald, E. et al. (2004). "Bariatric Surgery: a Systematic Review and Meta-Analysis". JAMA 292(14):1724-1737 ("Bariatric surgery in morbidly obese individuals reverses, eliminates, or significantly ameliorates diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea. These benefits occur in the majority of patients who undergo surgery")

Cummings, E. David et al. (2002). "Plasma Ghrelin Levels after Diet Induced Weight Loss or Gastric Bypass Surger". N. Engl J. Med. 346:1623-1630 ("If circulating ghrelin participates in long-term regulation of body weight, its level should increase with weight loss as part of the compensatory response to an energy deficit. In contrast, gastric bypass may disrupt ghrelin secretion by isolating ghrelin-producing cells from direct contact with ingested nutrients, which normally regulate ghrelin levels, and this effect may contribute to the efficacy of the procedure in reducing weight")

Frige', F. et al. (2009). "Batriatic Surgery in Obesity: Changes of Glucose & Lipid Metabolism Correlate with Changes of Fat Mass". Nutrition, Metabolism, & Cardiovascular Diseases 19:198-204 ("Both BIBP [biliary intestinal bypass] and LAGB [laporoscopic gastric binding] were highly effective in reducing BMI, with BIBP superior to LAGB in reducing FM [fat mass] but not FFM [fat free mass]. Metabolic effects were mostly proportional to FM decrease but not to FFM decrease")

Holdstock, C. et al. (2003). "Ghrelin and Adipose Tissue Regulatory Peptides: Effect of Gastric Bypass Surgery in Obese Humans". The Journal of Clinical Endocrinology and Metabolism" 88(7):3177-3183 ("Ghrelin levels in rats have been reported to be 80% lower after fundectomy and gastrectomy, and gastrectomy patients experienced a 65% decrease, demonstrating the stomach as the major source of circulating ghrelin. A recent study reported that ghrelin levels were lower in five gastric bypass surgery patients than in five BMI-matched obese subjects, who had completed a 6-month dietary weight loss program. The low levels of ghrelin in the five RYGBP patients made the authors suggest that the disconnection of the stomach had led to hypoghrelinemia and speculate that the hypoghrelinemia would lessen appetite and improve the outcome of RYGBP")

Korner, J. et al. (2005). "Effects of Roux-en-Y Gastric Bypass Surgery on Fasting & Postprandial Concentrations of Plasma Ghrelin, Peptide YY, & Insulin". The Journal of Clinical Endocrinology and Metabolism 90(1):359-365 ("Fasting ghrelin concentrations have been shown to decrease further after RYGB, compared with either preoperative levels in prospective studies or with nonsurgical obese controls in cross-sectional studies")

Polyzogopoulou, E. V. et al. (2003). "Restoration of Euglycaemia and Normal Acute Insulin Response to Glucose in Obese Subjects with Type 2 Diabetes following Bariatric Surgery". Diabetes 52:1098-1103 ("Although weight loss can be achieved by low-calorie diet, exercise, behavior modification, and medical treatment, late weight gain has been an almost universal problem. Conversely Roux-en-Y gastric bypass (RYGBP) maintains a weight loss of ~33% of body weight for >10 years, a result associated with normalization of glucose levels in patients with impaired glucose tolerance (IGT) and type 2 diabetes, in the vast majority of the cases")