Imipenem

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Revision as of 09:26, 27 June 2010 by imported>Howard C. Berkowitz
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Impipenem is a synthetic broad-spectrum antibiotic, which contains a beta-lactam ring structure but is not considered a member of the penicillin or cephalosporin class. It is a frequent choice for treatment of infections involving multidrug-resistant bacteria, or multiple types of bacteria.

It is a "semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilistatin, a renal dipeptidase inhibitor."[1]