Beta 2-glycoprotein I

In physiology, beta 2-glycoprotein (apolipoprotein H) I is "a 44-kDa highly glycosylated plasma protein that binds phospholipids including cardiolipin; apolipoprotein E receptor; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with antiphospholipid antibodies".

Autoantibodies to beta 2-glycoprotein may be associated with systemic lupus erythematosus and antiphospholipid syndrome.