Cefpodoxime

cefpodoxime
IUPAC name: Synonyms: cefpodoxime proxetil Formula: C15H17N5O6S2
Uses:	antibiotic drug
Properties:	cephalosporin beta-lactam
Hazards:
Mass (g/mol): CAS #: 427.4554 82619-04-3

Cefpodoxime is a third-generation cephalosporin antibiotic useful against many Gram-postitive and Gram-negative bacteria, including enteric bacteria and other eubacteria. Cefpodoxime proxetil is an oral prodrug that becomes de-esterified into the cefpodoxime, the active metabolite.

Mechanism of action

Like other cephalosporins and peniciillins, cefpodoxime inhibits the proper formation of bacterial cells walls in the last stage of cell wall synthesis. Because cefpodoxime is stable against many beta-lactamases, many organisms that are resistant to penicillins and cephalosporins, due to their beta-lactamase production, may be susceptible to cefpodoxime. Some extended-spectrum beta-lactamases may inactivate cefpodoxime.

Brand names

• Vantin®
• Banan®
• Doxef®
• Orelox®
• Otreon®
• Podomexef®

The most up-to-date information about Cefpodoxime and other drugs can be found at the following sites.

• Cefpodoxime - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Cefpodoxime - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Cefpodoxime - Detailed information from DrugBank.