Cortical thickness
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In brain anatomy, cortical thickness is a global measure used to describe the combined thickness of the layers of the cerebral cortex. It is commonly determined from the grey matter set in segmented neuroimaging data. Its variation across the human brain follows small-world principles[1], and deviations thereof can be used as diagnostic indicators for brain disorders, e.g. in lissencephaly and Williams syndrome[2].
References
- ↑ He, Yong; Zhang J. Chen & Alan C. Evans (2007), "Small-World Anatomical Networks in the Human Brain Revealed by Cortical Thickness from MRI", Cerebral Cortex 17 (10): 2407-2419, DOI:10.1093/cercor/bhl149 [e]
- ↑ Thompson, Paul M.; Agatha D. Lee & Rebecca A. Dutton et al. (2005), "Abnormal Cortical Complexity and Thickness Profiles Mapped in Williams Syndrome", Journal of Neuroscience 25 (16): 4146–4158, DOI:10.1523/JNEUROSCI.0165-05.2005 [e]