Vitamin B-12 deficiency
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In medicine, vitamin B-12 deficiency, is a "nutritional condition produced by a deficiency of Vitamin B-12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis."[1]
Manifestations include pernicious anemia and subacute combined degeneration.
Diagnosis
The MCV is not accurate.[2]
References
- ↑ Anonymous (2024), Vitamin B-12 deficiency (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Seward SJ, Safran C, Marton KI, Robinson SH (1990). "Does the mean corpuscular volume help physicians evaluate hospitalized patients with anemia?". J Gen Intern Med 5 (3): 187-91. DOI:10.1007/BF02600530. PMID 2187961. Research Blogging.