Healthy obesity

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Although obesity is a major risk factor for cardiovascular disease and type 2 diabetes mellitus, about a third of obese individuals maintain healthy cardiometabolic profiles; this phenotype of healthy obesity may be linked to the location of adipose tissue and the metabolic characteristics of the fat. Some data also suggest that weight loss by healthy obese subjects may have an adverse impact on their favorable cardiometabolic profile. [1] [2]

References

  1. Lee CM et al. (2008) Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis J Clin Epidemiol 61:646-53 PMID 18359190
  2. Wildman RP (2009) Healthy obesity Curr Opin Clin Nutr Metab Care 12:438-43 PMID 19474713