Nitrile
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A nitrile is an organic compound containing a carbon triple bonded to nitrogen.
Synthesis
- The Sandmeyer reaction employing cuprous cyanide can be used to form nitriles from diazonium compounds.
- Aryl nitriles may be formed from aryl halides in the Rosenmund-von Braun reaction.
- The reaction of cyanide with aldehydes or ketones forms a cyanohydrin (ά-hydroxynitrile).
- Amides may be dehydrated to nitriles with a variety of reagents