Hyponatremia

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Diagnosis

Experienced physicians have difficulty in determining the underlying causes of hyponatremia.[1]

Treatment

Tolvaptan, a vasopressin receptor antagonist, can be used for hyponatremia.[2][3] However, vasopressin receptor antagonist may increase the frequency of rapid sodium correction although osmotic demyelination syndrome may not be increased.[3]

References

  1. Fenske W, Maier SK, Blechschmidt A, Allolio B, Störk S (2010). "Utility and limitations of the traditional diagnostic approach to hyponatremia: a diagnostic study.". Am J Med 123 (7): 652-7. DOI:10.1016/j.amjmed.2010.01.013. PMID 20609688. Research Blogging.
  2. (2009) Tolvaptan (Samsca) for Hyponatremia The Medical Letter
  3. 3.0 3.1 Rozen-Zvi B, Yahav D, Gheorghiade M, Korzets A, Leibovici L, Gafter U (2010). "Vasopressin receptor antagonists for the treatment of hyponatremia: systematic review and meta-analysis.". Am J Kidney Dis 56 (2): 325-37. DOI:10.1053/j.ajkd.2010.01.013. PMID 20538391. Research Blogging.