Brain natriuretic peptide
Jump to navigation
Jump to search
In medicine, brain natriuretic peptide (BNP)is "peptide that is secreted by the brain and the heart atria, stored mainly in cardiac ventricular myocardium. It can cause natriuresis; diuresis; vasodilation; and inhibits secretion of renin and aldosterone. it improves heart function. it contains 32 amino acids."[1]
An elevated BNP can detect heart failure:[2]
Sensitivity | Specificity | |
---|---|---|
BNP > 100 pg per milliliter | 90% | 76% |
BNP > 50 pg per milliliter | 97% | 62% |
References
- ↑ Anonymous (2024), Brain natriuretic peptide (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ 2.0 2.1 Maisel AS, Krishnaswamy P, Nowak RM, et al (July 2002). "Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure". N. Engl. J. Med. 347 (3): 161–7. DOI:10.1056/NEJMoa020233. PMID 12124404. Research Blogging.