Cefpodoxime: Difference between revisions

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imported>David E. Volk
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imported>David E. Volk
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== Mechanism of action ==
== Mechanism of action ==
Cefpodoxime is active against a wide spectrum of Gram-positive and Gram-negative bacteria. Cefpodoxime is stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and cephalosporins, due to their production of beta-lactamase, may be susceptible to cefpodoxime. Cefpodoxime is inactivated by certain extended spectrum beta-lactamases. The bactericidal activity of cefpodoxime results from its inhibition of cell wall synthesis.
Like other [[cephalosporin]]s and [[peniciillin]]s, cefpodoxime inhibits the proper formation of bacterial cells walls in the last stage of cell wall synthesis. Because cefpodoxime is stable against many beta-[[lactamase]]s, many organisms that are resistant to penicillins and cephalosporins, due to their beta-lactamase production, may be susceptible to cefpodoxime. Some extended-spectrum beta-lactamases may inactivate cefpodoxime.


== Brand names ==
== Brand names ==

Revision as of 11:40, 14 July 2008

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Cefpodoxime..jpg
cefpodoxime
IUPAC name:
Synonyms:
Formula: C15H17N5O6S2

 Uses: antibiotic drug

 Properties: cephalosporin beta-lactam

 Hazards:

Mass (g/mol): CAS #:
427.4554 82619-04-3


Cefpodoxime is a third-generation cephalosporin-based antibiotic useful against most Gram-postitive and Gram-negative bacteria.

Mechanism of action

Like other cephalosporins and peniciillins, cefpodoxime inhibits the proper formation of bacterial cells walls in the last stage of cell wall synthesis. Because cefpodoxime is stable against many beta-lactamases, many organisms that are resistant to penicillins and cephalosporins, due to their beta-lactamase production, may be susceptible to cefpodoxime. Some extended-spectrum beta-lactamases may inactivate cefpodoxime.

Brand names

  • Vantin®
  • Banan®
  • Doxef®
  • Orelox®
  • Otreon®
  • Podomexef®

The most up-to-date information about Cefpodoxime and other drugs can be found at the following sites.