Coagulation: Difference between revisions

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===Factor II deficiency===
===Factor II deficiency===
Deficiency of Factor II (prothrombin) leads to hypoprothrombinemia.


===Factor V deficiency===
===Factor V deficiency===

Revision as of 10:44, 11 January 2008

Coagulation is "the process of the interaction of blood coagulation factors that results in an insoluble fibrin clot."[1]

Disorders of coagulation

Blood coagulation disorders are "hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as coagulation protein disorders; blood platelet disorders; blood protein disorders or nutritional conditions."[2]

Factor II deficiency

Deficiency of Factor II (prothrombin) leads to hypoprothrombinemia.

Factor V deficiency

Factor V deficiency is a "(known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as Owren's disease or parahemophilia. It varies greatly in severity. Factor V deficiency is an autosomal recessive trait."[3]


Factor X deficiency

Factor X deficiency is a "blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. It is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption."[4]

References

  1. Anonymous. Blood coagulation. National Library of Medicine. Retrieved on 2008-01-10.
  2. Anonymous. Blood Coagulation Disorders. National Library of Medicine.
  3. Anonymous. Factor V Deficiency. National Library of Medicine.
  4. Anonymous. Factor X Deficiency. National Library of Medicine.