Antineoplastic agent/Related Articles: Difference between revisions
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==Subtopics== | ==Subtopics== | ||
===Alkylating agents=== | ===Alkylating agents=== | ||
====Nitrogen | ====[[Nitrogen mustards]]==== | ||
{{r|Cyclophosphamide}} | {{r|Cyclophosphamide}} | ||
{{r|Chlorambucil}} | {{r|Chlorambucil}} | ||
{{r|Melphalan}} | {{r|Melphalan}} | ||
{{r|Mechlorethamine}} | |||
{{r|Chlormethine}} | {{r|Chlormethine}} | ||
{{r|Ifosfamide}} | {{r|Ifosfamide}} | ||
{{r|Trofosfamide}} | {{r|Trofosfamide}} | ||
{{r|Prednimustine}} | {{r|Prednimustine}} | ||
====Alkyl sulfonates==== | ====Alkyl sulfonates==== | ||
{{r|busulfan}} | {{r|busulfan}} | ||
Line 23: | Line 25: | ||
{{r|mannosulfan}} | {{r|mannosulfan}} | ||
====Ethylene imines==== | ====Ethylene imines==== | ||
{{r|Thiotepa}} | |||
{{r|Triaziquone}} | |||
{{r|Carboquone}} | |||
====Nitrosoureas==== | ====Nitrosoureas==== | ||
{{r|Nitrosourea}} | |||
{{r|Carmustine}} | |||
{{r|Lomustine}} | |||
{{r|Semustine}} | |||
{{r|Streptozocin}} | |||
{{r|Fotemustine}} | |||
{{r|Nimustine}} | |||
{{r|Ranimustine}} | |||
====Epoxides==== | ====Epoxides==== | ||
{{r|retoglucid}} | |||
====Other alkylating agents==== | ====Other alkylating agents==== | ||
{{r|Dacarbazine}} | |||
{{r|Mitobronitol}} | |||
{{r|Pipobroman}} | |||
{{r|Temozolomide}} | |||
===Antimetabolites=== | ===Antimetabolites=== | ||
{{r|Antimetabolite}} | {{r|Antimetabolite}} | ||
====Folic acid analogues==== | |||
===Folic acid analogues=== | |||
{{r|Folic acid}} | {{r|Folic acid}} | ||
{{r|Folic acid | {{r|Folic acid antagonist}} | ||
{{r|Methotrexate}} | {{r|Methotrexate}} | ||
{{r|Raltitrexed}} | {{r|Raltitrexed}} | ||
{{r|Pemetrexed }} | {{r|Pemetrexed }} | ||
===Purine analogues=== | ====Purine analogues==== | ||
{{r|Purine analogue antimetabolite}} | {{r|Purine analogue antimetabolite}} | ||
{{r| mercaptopurine}} | {{r| mercaptopurine}} | ||
{{r|tioguanine}} | {{r|tioguanine}} | ||
Line 54: | Line 64: | ||
{{r|clofarabine}} | {{r|clofarabine}} | ||
{{r|nelarabine}} | {{r|nelarabine}} | ||
====Pyrimidine analogues==== | ====Pyrimidine analogues==== | ||
{{r|Pyrimidine analog antimetabolite}} | {{r|Pyrimidine analog antimetabolite}} | ||
{{r|cytarabine}} | {{r|cytarabine}} | ||
{{r|fluorouracil | {{r|fluorouracil}} | ||
{{r|tegafur | {{r|tegafur}} | ||
{{r|carmofur | {{r|carmofur}} | ||
{{r|gemcitabine | {{r|gemcitabine}} | ||
{{r|capecitabine | {{r|capecitabine}} | ||
{{r|azacitidine | {{r|azacitidine}} | ||
{{r|decitabine | {{r|decitabine}} | ||
===Plant alkaloids and other natural products=== | ===Plant alkaloids and other natural products=== | ||
==== Vinca alkaloids and analogues==== | ==== Vinca alkaloids and analogues==== | ||
{{r|Vinca alkaloid}} | {{r|Vinca alkaloid}} | ||
{{r|Vincristine}} | {{r|Vincristine}} | ||
{{r|Vinblastine}} | {{r|Vinblastine}} | ||
{{r|Vindesine}} | |||
{{r|Vinorelbine}} | |||
ATC/DDD group L01CA. | ATC/DDD group L01CA. | ||
====Podophyllotoxin derivatives==== | ====Podophyllotoxin derivatives==== | ||
{{r|Podophyllin}} | |||
{{r|Etoposide}} | |||
{{r|Teniposide}} | |||
====Colchicine derivatives==== | ====Colchicine derivatives==== | ||
{{r|Colchicine}} | {{r|Colchicine}} | ||
{{r|Demecolcine}} | |||
====Taxanes==== | ====Taxanes==== | ||
{{r|Paclitaxel}} | |||
{{r|Docetaxel}} | |||
{{r|Paclitaxel poliglumex}} | |||
====Other plant alkaloids and natural products==== | ====Other plant alkaloids and natural products==== | ||
{{r|Trabectedin}} | |||
===Cytotoxic antibiotics and related substances=== | ===Cytotoxic antibiotics and related substances=== | ||
====Actinomycines==== | ====Actinomycines==== | ||
{{r|Dactinomycin}} | |||
====Anthracyclines and related substances==== | ====Anthracyclines and related substances==== | ||
{{r|Doxorubicin}} | |||
{{r|Daunorubicin}} | |||
{{r|Epirubicin}} | |||
{{r|Aclarubicin}} | |||
{{r|Zorubicin}} | |||
{{r|Idarubicin}} | |||
{{r|Mitoxantrone}} | |||
{{r|Pirarubicin}} | |||
{{r|Valrubicin}} | |||
====Other cytotoxic antibiotics==== | ====Other cytotoxic antibiotics==== | ||
{{r|Bleomycin}} | |||
{{r|Plicamycin}} | |||
{{r|Mitomycin}} | |||
{{r|Ixabepilone}} | |||
===Other antineoplastic agents=== | ===Other antineoplastic agents=== | ||
Line 119: | Line 139: | ||
=====Anti-EpCAM===== | =====Anti-EpCAM===== | ||
{{r|Edrecolomab}}is monclonal antibody against EpCAM (Entrez protein). Edrecolomab is a "anticolorectal carcinoma antibody for treatment of advanced colorectal carcinoma".[9] | {{r|Edrecolomab}}is monclonal antibody against EpCAM (Entrez protein). Edrecolomab is a "anticolorectal carcinoma antibody for treatment of advanced colorectal carcinoma".[9] | ||
=====Anti-ERBB2==== | =====Anti-ERBB2===== | ||
{{r|Trastuzumab}}"HER2 (Entrez protein) antibody that lengthens remission time in metastatic breast cancer." | {{r|Trastuzumab}}"HER2 (Entrez protein) antibody that lengthens remission time in metastatic breast cancer." | ||
Line 132: | Line 152: | ||
{{r|Gemtuzumab}}is an "anti-CD33 (Entrez protein) antibody calicheamicin conjugate".[13] | {{r|Gemtuzumab}}is an "anti-CD33 (Entrez protein) antibody calicheamicin conjugate".[13] | ||
=====Anti-CD52 | =====Anti-CD52===== | ||
{{r|Alemtuzumab}} | |||
=====Anti-VEGF===== | =====Anti-VEGF===== | ||
{{r|Bevacizumab}}is an "anti-VEGF (Entrez protein) monoclonal antibody consisting of humanized murine antibody with antigen-binding, complementary-determining regions from murine VEGF".[15] | {{r|Bevacizumab}}is an "anti-VEGF (Entrez protein) monoclonal antibody consisting of humanized murine antibody with antigen-binding, complementary-determining regions from murine VEGF".[15] | ||
===Sensitizers used in photodynamic/radiation therapy=== | ===Sensitizers used in photodynamic/radiation therapy=== | ||
{{r|porfimer sodium}} | |||
{{r|methyl aminolevulinate}} | |||
{{r|aminolevulinic acid}} | |||
{{r|temoporfin}} | |||
{{r|efaproxiral}} | |||
===[[Protein kinase]] inhibitors=== | |||
===Protein kinase inhibitors=== | {{r|Imatinib}} | ||
{{r|Gefitinib}} | |||
{{r|Erlotinib}} | |||
{{r|Sunitinib}} | |||
{{r|Sorafenib}} | |||
{{r|Dasatinib}} | |||
{{r|Lapatinib}} | |||
{{r|Nilotinib}} | |||
{{r|Temsirolimus}} | |||
==Other related topics== | ==Other related topics== | ||
{{r|Antiemetic}} | {{r|Antiemetic}} | ||
{{r|Protein kinase}} | |||
==Articles related by keyphrases (Bot populated)== |
Latest revision as of 11:00, 11 July 2024
- See also changes related to Antineoplastic agent, or pages that link to Antineoplastic agent or to this page or whose text contains "Antineoplastic agent".
Parent topics
- Cancer [r]: A generic term for a large group of diseases that can affect any part of the body; one defining feature is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs. [e]
- Immunology [r]: The study of all aspects of the immune system in all animals. [e]
- Oncology [r]: The medical diagnosis and treatment of neoplasia, using pharmacologic, radiation, immunologic and surgical techniques; relevant formal subspecialties are medical oncology in internal medicine and radiation oncology in radiology; surgeons also may specialize in neoplasia [e]
Subtopics
Alkylating agents
Nitrogen mustards
- Cyclophosphamide [r]: A medication and immunosuppressive agent used to treat lymphoma and leukemia. [e]
- Chlorambucil [r]: Add brief definition or description
- Melphalan [r]: Add brief definition or description
- Mechlorethamine [r]: Add brief definition or description
- Chlormethine [r]: Add brief definition or description
- Ifosfamide [r]: Add brief definition or description
- Trofosfamide [r]: Add brief definition or description
- Prednimustine [r]: Add brief definition or description
Alkyl sulfonates
- Busulfan [r]: Add brief definition or description
- Treosulfan [r]: Add brief definition or description
- Mannosulfan [r]: Add brief definition or description
Ethylene imines
- Thiotepa [r]: Add brief definition or description
- Triaziquone [r]: Add brief definition or description
- Carboquone [r]: Add brief definition or description
Nitrosoureas
- Nitrosourea [r]: Add brief definition or description
- Carmustine [r]: Also known as BNCU for bis-chloronitrosourea, a nitrosourea-derived alkylating agent used in the therapy of lymphomas and gliomas; administered both intravenously and as a surgically implanted drug-releasing wafer [e]
- Lomustine [r]: Add brief definition or description
- Semustine [r]: Add brief definition or description
- Streptozocin [r]: Add brief definition or description
- Fotemustine [r]: Add brief definition or description
- Nimustine [r]: Add brief definition or description
- Ranimustine [r]: Add brief definition or description
Epoxides
Other alkylating agents
- Dacarbazine [r]: Add brief definition or description
- Mitobronitol [r]: Add brief definition or description
- Pipobroman [r]: Add brief definition or description
- Temozolomide [r]: Add brief definition or description
Antimetabolites
Folic acid analogues
- Folic acid [r]: Add brief definition or description
- Folic acid antagonist [r]: Add brief definition or description
- Methotrexate [r]: Add brief definition or description
- Raltitrexed [r]: Add brief definition or description
- Pemetrexed [r]: Add brief definition or description
Purine analogues
- Purine analogue antimetabolite [r]: Add brief definition or description
- Mercaptopurine [r]: Add brief definition or description
- Tioguanine [r]: Add brief definition or description
- Cladribine [r]: Add brief definition or description
- Fludarabine [r]: Add brief definition or description
- Clofarabine [r]: Add brief definition or description
- Nelarabine [r]: Add brief definition or description
Pyrimidine analogues
- Pyrimidine analog antimetabolite [r]: Add brief definition or description
- Cytarabine [r]: Add brief definition or description
- Fluorouracil [r]: Add brief definition or description
- Tegafur [r]: Add brief definition or description
- Carmofur [r]: Add brief definition or description
- Gemcitabine [r]: Add brief definition or description
- Capecitabine [r]: Add brief definition or description
- Azacitidine [r]: Add brief definition or description
- Decitabine [r]: Add brief definition or description
Plant alkaloids and other natural products
Vinca alkaloids and analogues
- Vinca alkaloid [r]: Add brief definition or description
- Vincristine [r]: Add brief definition or description
- Vinblastine [r]: Add brief definition or description
- Vindesine [r]: Add brief definition or description
- Vinorelbine [r]: Add brief definition or description
ATC/DDD group L01CA.
Podophyllotoxin derivatives
- Podophyllin [r]: Add brief definition or description
- Etoposide [r]: Add brief definition or description
- Teniposide [r]: Add brief definition or description
Colchicine derivatives
- Colchicine [r]: Add brief definition or description
- Demecolcine [r]: Add brief definition or description
Taxanes
- Paclitaxel [r]: Add brief definition or description
- Docetaxel [r]: Add brief definition or description
- Paclitaxel poliglumex [r]: Add brief definition or description
Other plant alkaloids and natural products
Actinomycines
- Doxorubicin [r]: Add brief definition or description
- Daunorubicin [r]: Add brief definition or description
- Epirubicin [r]: Add brief definition or description
- Aclarubicin [r]: Add brief definition or description
- Zorubicin [r]: Add brief definition or description
- Idarubicin [r]: Add brief definition or description
- Mitoxantrone [r]: Add brief definition or description
- Pirarubicin [r]: Add brief definition or description
- Valrubicin [r]: Add brief definition or description
Other cytotoxic antibiotics
- Bleomycin [r]: Add brief definition or description
- Plicamycin [r]: Add brief definition or description
- Mitomycin [r]: Add brief definition or description
- Ixabepilone [r]: Add brief definition or description
Other antineoplastic agents
ATC/DDD group L01X.
Platinum compounds
- Cisplatin [r]: Add brief definition or description
- Carboplatin [r]: Add brief definition or description
ATC/DDD group L01XA.
Methylhydrazines
ATC/DDD group L01XB.
Monoclonal antibodies
ATC/DDD group L01XC. Examples include:
Anti-EGRF
- Epidermal growth factor [r]: Add brief definition or description
- Panitumumab [r]: Add brief definition or descriptionan "antibody that blocks receptors for epidermal growth factor (Entrez protein); approved for advanced colon cancer".[8]
Anti-EpCAM
- Edrecolomab [r]: Add brief definition or descriptionis monclonal antibody against EpCAM (Entrez protein). Edrecolomab is a "anticolorectal carcinoma antibody for treatment of advanced colorectal carcinoma".[9]
Anti-ERBB2
- Trastuzumab [r]: Add brief definition or description"HER2 (Entrez protein) antibody that lengthens remission time in metastatic breast cancer."
Anti-CD3 and anti-EpCAM
- Catumaxomab [r]: Add brief definition or description Is a monoclonal antibody against CD3 (Entrez protein)and EpCAM (Entrez protein). "Extracorporeal PBMNC coating with catumaxomab may be an option to control intravascular cytokine release induced by therapeutic antibodies".[11]
Anti-MS4A1 (CD20 antigen)
- Rituximab [r]: Add brief definition or description is a "genetically engineered anti-CD20 (Entrez protein) antibody for the treatment of B-cell lymphoma".[12]
Anti-SIGLEC3 (CD33)
- Gemtuzumab [r]: Add brief definition or descriptionis an "anti-CD33 (Entrez protein) antibody calicheamicin conjugate".[13]
Anti-CD52
Anti-VEGF
- Bevacizumab [r]: Add brief definition or descriptionis an "anti-VEGF (Entrez protein) monoclonal antibody consisting of humanized murine antibody with antigen-binding, complementary-determining regions from murine VEGF".[15]
Sensitizers used in photodynamic/radiation therapy
- Porfimer sodium [r]: Add brief definition or description
- Methyl aminolevulinate [r]: Add brief definition or description
- Aminolevulinic acid [r]: Add brief definition or description
- Temoporfin [r]: Add brief definition or description
- Efaproxiral [r]: Add brief definition or description
Protein kinase inhibitors
- Imatinib [r]: Add brief definition or description
- Gefitinib [r]: Add brief definition or description
- Erlotinib [r]: Add brief definition or description
- Sunitinib [r]: Add brief definition or description
- Sorafenib [r]: Add brief definition or description
- Dasatinib [r]: Add brief definition or description
- Lapatinib [r]: Add brief definition or description
- Nilotinib [r]: Add brief definition or description
- Temsirolimus [r]: Add brief definition or description
- Antiemetic [r]: Add brief definition or description
- Protein kinase [r]: Add brief definition or description