Protein kinase/Related Articles

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• Adenosine triphosphate [r]: A molecule sometimes called the "energy currency" of a cell ^[e]
• Antineoplastic agent [r]: Drug that prevents the development, maturation, or spread of neoplastic cells. ^[e]
• Cyclic AMP [r]: An adenine nucleotide that is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. ^[e]
• Cyclic GMP [r]: A guanine nucleotide that is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. ^[e]
• Drug discovery [r]: Process by which pharmaceuticals are discovered and/or designed. ^[e]
• G-protein-coupled receptor kinase [r]: A family of protein kinases which regulate the activity of G protein-coupled receptors (GPCRs) by phosphorylating their intracellular domains after their associated G proteins have been released and activated. ^[e]
• G-protein-coupled receptor [r]: Protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. ^[e]
• Phospholipase [r]: Enzyme of four major classes, that hydrolyzes phospholipids into fatty acids and other lipophilic substances. ^[e]
• Protein [r]: A polymer of amino acids; basic building block of living systems. ^[e]
• Second messenger system [r]: Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. ^[e]
• Signal transduction [r]: The intercellular or intracellular transfer of information (biological activation/inhibition) through a signal pathway. ^[e]