Talk:Venereal disease: Difference between revisions
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Schwartz RS. Paul Ehrlich's magic bullets. [Biography. Historical Article. Journal Article] New England Journal of Medicine. 350(11):1079-80, 2004 Mar 11. | Schwartz RS. Paul Ehrlich's magic bullets. [Biography. Historical Article. Journal Article] New England Journal of Medicine. 350(11):1079-80, 2004 Mar 11. | ||
UI: 15014180 | UI: 15014180 "Ehrlich's third triumph was in chemotherapy, another term that he coined. Reapplying the notion of the magic bullet that he had conceived in characterizing antibodies, he developed the concept of a chemical that binds to and specifically kills microbes or tumor cells. The culmination of this work was arsphenamine (Salvarsan, or compound 606), the first effective treatment for syphilis. At a meeting in Wiesbaden in 1910, Ehrlich and his colleagues announced the experimental and clinical effects of their treatment of syphilis with this compound. The result was an avalanche of demands for the drug, which the Hochst Chemical Works began to manufacture on a large scale. More than 65,000 doses were distributed free of charge. Arsphenamine was the first in the line of antibiotics - sulfamidochrysoidine (prontosil), a sulfonamide discovered in 1932 by Gerhard Domagk, was the next one - that revolutionized medicine." | ||
Morton RS. Rashid S. "The syphilis enigma": the riddle resolved?. [Historical Article. Journal Article] Sexually Transmitted Infections. 77(5):322-4, 2001 Oct. | Morton RS. Rashid S. "The syphilis enigma": the riddle resolved?. [Historical Article. Journal Article] Sexually Transmitted Infections. 77(5):322-4, 2001 Oct. | ||
Revision as of 16:10, 5 May 2007
Ths article will cover, in detail, the traditionally defined venereal diseases, rather than all diseases (STD) that are epidemiologically noted to be prevalent in sexually promiscuous people or can possibly be spread through sexual contact. In this way, the difference between the spread of a disease like hepatitis B and syphilis can be better understood by the reader who reads this article , and Sexually transmitted diseases. Hopefully, by the time they are both fully written.Nancy Sculerati 08:25, 5 May 2007 (CDT)
references - with notes
George R Kinghorn Chapter 75 – Syphilis in Cohen & Powderly: Infectious Diseases, 2nd ed. copyright 2004
Waugh M. The centenary of Treponema pallidum: on the discovery of Spirochaeta pallida. [Historical Article. Journal Article] International Journal of STD & AIDS. 16(9):594-5, 2005 Sep.
UI: 16176623
Schwartz RS. Paul Ehrlich's magic bullets. [Biography. Historical Article. Journal Article] New England Journal of Medicine. 350(11):1079-80, 2004 Mar 11. UI: 15014180 "Ehrlich's third triumph was in chemotherapy, another term that he coined. Reapplying the notion of the magic bullet that he had conceived in characterizing antibodies, he developed the concept of a chemical that binds to and specifically kills microbes or tumor cells. The culmination of this work was arsphenamine (Salvarsan, or compound 606), the first effective treatment for syphilis. At a meeting in Wiesbaden in 1910, Ehrlich and his colleagues announced the experimental and clinical effects of their treatment of syphilis with this compound. The result was an avalanche of demands for the drug, which the Hochst Chemical Works began to manufacture on a large scale. More than 65,000 doses were distributed free of charge. Arsphenamine was the first in the line of antibiotics - sulfamidochrysoidine (prontosil), a sulfonamide discovered in 1932 by Gerhard Domagk, was the next one - that revolutionized medicine."
Morton RS. Rashid S. "The syphilis enigma": the riddle resolved?. [Historical Article. Journal Article] Sexually Transmitted Infections. 77(5):322-4, 2001 Oct. UI: 11588273
Green T. Talbot MD. Morton RS. The control of syphilis, a contemporary problem: a historical perspective. [Historical Article. Journal Article] Sexually Transmitted Infections. 77(3):214-7, 2001 Jun. UI: 11402234