Lipostatic hypothesis

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In 1953, Kennedy [1] proposed what became known as the lipostatic hyothesis. Specifically, he postulated the existence, in the hypothalamus, of a centre that was sensitive to the concentration of metabolites in the circulation, which prevented "an overall surplus of energy intake over expenditure."


References

  1. Kennedy GC (1953) The role of depot fat in the hypothalamic control of food intake in the rat Proc R Soc Lond B Biol Sci 140:578-92 [1]

Sophie Rajska 11:21, 10 October 2011 (UTC)

www.maximivanov.com/nutrition2.doc

http://ajpregu.physiology.org/content/286/1/R14.full

http://ajpregu.physiology.org/content/292/1/R37.full

<ref>http://www.news-medical.net/health/Hypothalamus-and-Food-Intake.aspx<ref>