Adrenergic uptake inhibitor: Difference between revisions
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In [[medicine]] and [[pharmacology]], '''adrenergic uptake inhibitors''' are [[medication]]s that "block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The [[tricyclic antidepressant]]s and [[amphetamine]]s are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of [[serotonin]]."<ref>{{MeSH}}</ref> | In [[medicine]] and [[pharmacology]], '''adrenergic uptake inhibitors''' are [[medication]]s that "block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The [[tricyclic antidepressant]]s and [[amphetamine]]s are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of [[serotonin]]."<ref>{{MeSH}}</ref> | ||
==Medical uses== | |||
===Depression=== | |||
[[Depression]] may be due to the monoamine-deficiency hypothesis, which is a "deficiency in [[serotonin]] or [[norepinephrine]] neurotransmission in the brain."<ref name="pmid18172175">{{cite journal |author=Belmaker RH, Agam G |title=Major depressive disorder |journal=N. Engl. J. Med. |volume=358 |issue=1 |pages=55–68 |year=2008 |pmid=18172175 |doi=10.1056/NEJMra073096|url=http://content.nejm.org/cgi/content/full/358/1/55}}</ref> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 07:52, 19 December 2008
In medicine and pharmacology, adrenergic uptake inhibitors are medications that "block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin."[1]
Medical uses
Depression
Depression may be due to the monoamine-deficiency hypothesis, which is a "deficiency in serotonin or norepinephrine neurotransmission in the brain."[2]
References
- ↑ Anonymous (2024), Adrenergic uptake inhibitor (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Belmaker RH, Agam G (2008). "Major depressive disorder". N. Engl. J. Med. 358 (1): 55–68. DOI:10.1056/NEJMra073096. PMID 18172175. Research Blogging.